Pilot and Feasibility Award Program
2017 Pilot and Feasibility Awards of the Stanford DRC
Based on our recent Pilot and Feasibility request for applications we received 37 applications. On behalf of the Stanford Diabetes Research Center, congratulations to the 2017 Stanford DRC P&F award recipients!
The Stanford Diabetes Research Center is committed to providing support for original research related to diabetes in all disciplines. Our goal is to support, enhance and foster new ideas that will improve how we understand, diagnose, treat and care for diabetes and its complications. The P&F program is a DRC hallmark designed to meet this goal.
The submitted proposals were from multiple disciplines representing a wide range of biology and clinical medicine. These included proposals from investigators in the Departments of Medicine, Pediatrics, Psychiatry and Behavioral Sciences, Surgery, Obstetrics and Gynecology, Radiology, Ophthalmology, Pathology, Anesthesiology, the Cardiovascular Institute, Genetics, Bioengineering, Microbiology and Immunology, Chemical Systems Biology and Molecular & Cellular Physiology. A total of ten proposals were selected for funding from this year's P&F competition, six with funds from the DRC and four by DRC arrangements with CVI Seed Program. We anticipate another P&F competition in the autumn of 2018; please watch for the Request for Applications.
Thank you to all for your submissions, and congratulations again to this year's awardees.
Justin Annes, MD PhD | Assistant Professor, Department of Medicine (Endocrinology)
Collaborators: Or Gozani, MD PhD
“Mitochondrial Dysfunction Promotes b-Cell Failure and diabetes via a Previously Unrecognized Mechanism: Protein Hyper-Succinylation”
Eric Appel, PhD | Assistant Professor, Materials Science and Engineering
Collaborators: Bruce Buckingham, MD and David Maahs, MD PhD
“Novel ultra-fast insulin formulations for diabetes treatment”
Jennifer Lee, PhD | Associate Professor, Medicine (Endocrinology)
Collaborators: Phil Tsao, PhD and Jan Liphardt, PhD
“Diabetes Precision Phenotyping & Outcomes Prediction in Health Care”
Everett Meyer, MD PhD | Assistant Professor Department of Medicine (Bone Marrow Transplantation)
“Therapeutic targeting of islet-infiltrating invariant NKT cells in diabetes to promote islet tolerance”
Latha Palaniappan, MD MS | Clinical Professor, Department of Medicine (General Medicine)
Collaborators: Mike Snyder, PhD, Holden Maecker, PhD, Francois Haddad, MD and Utkan Demirci, PhD
“Elucidating the mechanisms of Diabetic Cardiomyopathy through Exosome Profiling, A Diabetes Research Center Collaborative Initiative”
Tom Soh, PhD | Professor, Electrical Engineering
Collaborators: Jelena Vuckovic, PhD and Seung Kim, MD PhD
“Real-time biosensor for continuous in vivo detection of glucose”
Avnesh Thakor, MD PhD | Assistant Professor, Radiology
Project title: A novel collagen based cryogel bioscaffold that generates oxygen and promotes angiogenesis for islet transplantation
Xiaolin Zheng, PhD | Associate Professor Mechanical Engineering
“Breath Acetone Sensor towards Non-invasive Diabetic Monitoring”
Fredric B. Kraemer, M.D. receiving his Bachelor's degree in Chemistry from Emory University in 1970 and his M.D. from New York University in 1974. He was a house officer in Internal Medicine at Kings County/Downstate Medical Center (1974-1978) and a postdoctoral fellow in Endocrinology at Stanford University (1978-1982). He joined the faculty in the Department of Medicine at Stanford in 1983, with an appointment at the Palo Alto VA Hospital in 1988. Dr. Kraemer currently holds the Stanford University Professorship in Endocinology and is the Chief of the Divison of Endocrinology, Gerontology and Metabolism, as well as a staff physician at the VA Palo Alto Health Care System. He was Associate Chief of Staff for Research and Development at the VA Palo Alto Health Care System from 2002-2007. His clinical and research interests have been focused on diabetes and cellular lipid metabolism. Dr. Kraemer's research program has been supported throughout his career by grants from the NIH and the Department of Veterans Affairs. He has won several awards including a Special Emphasis Research Career Award from the NIH, a SmithKline Beecham Junior Faculty Award in Diabetes, and an Arteriosclerosis Special Recognition Award from the Council on Arteriosclerosis, Thrombosis and Vascular Biology of the American Heart Association. Dr. Kraemer has served as president of the Western States Affiliate of the American Hearth Association, on the Scientific Advisory Committee of the University of California Tobacco-Related Disease Program, and the University of Minnesota Obesity Center, and the Advisory Board of the Deuel Conference on Lipids. In addition, he has served on a number of grant review boards for VA, NIH, American Diabetes Association and American Heart Association.