2016 Pilot and Feasibility Awards of the Stanford DRC

Based on our 2016 Pilot and Feasibility request for applications we received 37 applications. The submitted proposals were from multiple disciplines representing a wide range of biology and clinical medicine. These included proposals from investigators in the Departments of Medicine, Pediatrics, Psychiatry and Behavioral Sciences, Surgery, Obstetrics and Gynecology, Radiology, Ophthalmology, Pathology, Anesthesiology, the Cardiovascular Institute, Genetics, Bioengineering, Microbiology and Immunology, Chemical Systems Biology and Molecular & Cellular Physiology. A total of ten proposals were selected for funding from this year's P&F competition, six with funds from the DRC and four by DRC arrangements with CVI Seed Program.

Vivek Bhalla MD | Assistant Professor of Medicine (Nephrology)
Collaborators: Michael Snyder, PhD, Latha Palaniappan, MD
"Validation of cell-free RNA associated with human diabetic kidney disease"

Jennifer Cochran PhD | Associate Professor of Bioengineering, and by courtesy, of Chemical Engineering
"Engineering agonists of the glucagon-like peptide-1 receptor with novel pharmacological properties for the study and therapeutic control of diabetes"

Eric Gross, MD | Assistant Professor of Anesthesiology, Perioperative and Pain Medicine
"Generation of endothelial cells resistant to hyperglycemia-induced endothelial cell dysfunction"

Won Hee Lee, PhD | Instructor, Cardiovascular Institute
Collaborators: Kari Nadeau, PhD, Sang Ging Ong, PhD
"Assessing the potential health risk of e-cigarettes in diabetes"

Joyce Liao, MD PhD | Assistant Professor of Ophthalmology
Collaborator: Cornelia Weyand, MD PhD
"Treatment of vision loss due to optic nerve ischemia in diabetes"

Elena Matsa, PhD | Instructor, Cardiovascular Institue
Collaborators: Kenneth Mahaffey MD, Michael P. Snyder, PhD
"Identification of genetic variation determining patient-specific responses to anti-diabetic drugs"

Tracey McLaughlin, MD | Associate Professor of Medicine (Endocrinology)
Collaborators: Nazish Sayed, MD, PhD, Ian Chen, MD, PhD
"Predicting Cardiovascular Benefits of Anti-diabetic Drugs"

Nadine Nagy, PhD | Instructor, Department of Medicine
Collaborators: Paul Bollyky MD, PhD, Adam Frymoyer, MD, Jayakumar Rajadas, PhD
"The development of 4-methylumbelliferone analogs to prevent autoimmune diabetes"

Diana Naranjo, MD | Research Assistant Professor, Psychiatry and Behavioral Sciences
Collaborator: Korey Hood, PhD
"Optimizing uptake and use of closed loop automated insulin delivery systems through virtual reality"

Mary Teruel, PhD | Assistant Professor, Chemical Systems Biology
Collaborator: Rajat Roatgi, MD
"Understanding the role of FABP4 in regulating adipogenesis and adipocyte function"