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New Study from the NIH Integrated Islet Distribution Program and DRCs Reveals How Human Pancreatic Islet Cell Composition Shapes Diabetes Risk
SDRC member Anna Gloyn and others lead efforts mapping diabetes risk to pancreatic islet cell heterogeneity and genes that could drive variation in blood sugar regulation.
Why Ozempic May Not Work for Everyone: SDRC Investigator Anna Gloyn and Colleagues Uncover a Genetic Resistance to GLP-1 Drugs
A decade-long study finds that roughly 1 in 10 people carry genetic variants that may blunt the blood sugar-lowering effects of widely used diabetes medications — raising new questions about precision medicine in diabetes care. Read more...
A Python-Derived Molecule Called pTOS Could Point to New Weight-Loss Pathways
SDRC Investigator Dr. Jonathan Long's latest research reveals how pTOS — a metabolite that surges dramatically in snake blood after a meal — may offer a novel approach to appetite regulation with implications for diabetes care.
SDRC members highlighted in the new "Walk with Me" video series
If you’ve ever wondered what happens inside a research lab — and why it matters — this is a look behind the scenes. In Walk with Me, faculty including SDRC members C. Bertozzi, J. Wu and SK Kim talk about the questions guiding their work and the impact they hope to achieve.
Breakthrough Study led by Edgar Engleman Identifies Key Immune Switch That Could Revolutionize Treatments for Autoimmunity and other diseases
Researchers discover how erythropoietin (EPO) signaling in dendritic cells (cDC1s) regulates immune tolerance, offering new pathways for treating diseases like diabetes and other autoimmune conditions.
A decade-long study finds that roughly 1 in 10 people carry genetic variants that may blunt the blood sugar-lowering effects of widely used diabetes medications — raising new questions about precision medicine in diabetes care. Read more...