List of Ongoing Diabetes-related Trials That Are Actively Recruiting Patients

For Pediatric Endocrinology studies, please see: https://med.stanford.edu/pedsendo/research.html
DESIGNATE Information:
-Ages 8 – 45
-Eligibility – T1D
-New Onset within 18 months of diagnosis
-30 adult participants must be enrolled and assessed prior to enrollment of pediatric subjects
-Study Duration – 12 months
-The primary objective is to identify a safe, metabolically favorable, dosing regimen for siplizumab in patients with type 1 diabetes that induces changes in T cell phenotypes observed with alefacept therapy in new onset T1DM. The secondary objectives are to: 1. Assess the safety profile of siplizumab in recently diagnosed T1DM. 2. Assess the effects of siplizumab on residual beta cell function in recently diagnosed T1DM participants.
Please contact Trudy Esrey at tesrey@stanford.edu for more information.
Diabetes Wellness Teen Study The Diabetes Wellness Teen Study is investigating risk factors that predict future onset of eating disorders in adolescents with type 1 diabetes. If you are between the ages of 11-17, have type 1 diabetes, and use a continuous glucose monitor you may be eligible to participate! You could earn up to $125. All study activities are completely virtual!

If interested, use the link below and a member of the research team will reach out to you with more information!

https://redcap.link/DWTSinterest

Learn more:
https://stanforddwts.weebly.com/
shirazh@stanford.edu
650-272-0461
For complaints, concerns, or participant's rights, contact 1-866-680-2906.

Ignite Weight Loss Program (Research Study) Are you (1) interested in losing weight, (2) 18 years or older, (3) a smartphone user, and (4) living in the United States?

If so, you may be eligible to participate in a new Stanford University research study that evaluates a weight loss program. We are recruiting adults who are overweight who are interested in improving health through changes in diet and physical activity. All participants will receive a 10-week weight loss program. Study visits are done remotely. Participants will be compensated for their time.

To see if you're eligible, go to https://redcap.link/ignite
Improving Glycemic Control using a Virtual Weight Control Program and Continuous Glucose Monitoring in Adults with Type 2 Diabetes (VITAL-CGM) We are looking for participants ages 18-69 with type 2 diabetes to join our weight loss study. Participants will receive a free diabetes-tailored Weight Watchers app for 12 months, free access to continuous glucose monitoring, free virtual group or 1 on 1 weight loss sessions with trained professionals, and compensation between $50 to $75 per visit to Stanford University. To learn more about this study, please follow the QR Code or contact Nicole Turk at nturk@stanford.edu.
Effect of Meal Timing on Glucose Control, Body Temperature, Microbiome, and Sleep Physiology This research study uses digital health monitoring system combined with wearable technology to study the effect of changing time of meals, caloric distribution per meal, and meal composition on blood sugars, body temperature, metabolism, microbiome and sleep physiology. For more information about this study, please visit here.
DREAM DREAM is a study to find out how frequently people with acute pancreatitis develop diabetes. High blood sugar (blood glucose) is a known complication of acute pancreatitis. Sometimes high blood sugars can last a few weeks after acute pancreatitis and get better. However, sometimes high blood sugars may not improve after acute pancreatitis and diabetes is diagnosed. Diabetes can also appear later, a year or more after acute pancreatitis. Little data is available on how often or why diabetes occurs after acute pancreatitis. The DREAM study will help to better understand diabetes after acute pancreatitis and who is at increased risk of developing it, as well as the different types of diabetes that develop after acute pancreatitis.

For more information, please contact:
Lorena Pineda
Email: ljpineda@stanford.edu
Phone : 650-725-2767
Project Health If you are between the ages of 18-65, have been diagnosed with prediabetes, and live in the Califronia Bay Area, then we invite you to participate in Project Health! Participants will be randomized to one of two interventions designed to improve HbA1c, eating habits, and exercise habits to reduce onset of Type 2 Diabetes. You could earn up to $150 for completion of all study tasks.

To learn more, please visit https://stanfordprojecthealth.weebly.com/, or contact the study coordinator at projecthealth2@stanford.edu or 650-285-2049.

Please see flyer here.
ONBOARD: Overcoming Barriers and Obstacles to Adopting Diabetes Devices The Overcoming Barriers and Obstacles to Adopting Diabetes (ONBOARD) study is seeking participants for our research study about barriers to uptake of continuous glucose monitoring (CGM) in adults with type 1 diabetes. You may be eligible for this study if you are:
  • Between 18 and 50 years of age
  • Clinically diagnosed with type 1 diabetes
  • Not currently using a continuous glucose monitor or not regularly using in the past 6 months, but willing to start
If you answered yes to all of the above and are interested in participating in this study, please fill out this screener survey: https://redcap.link/uwtw619n

If you would like more information about this study, please contact a member of the study team at 650-725-3955 or onboardstudy@stanford.edu

For participant rights questions, contact 1-866-680-2906.
Predictive and Diagnostic Biomarkers for Diabetic Foot Ulcers – c-myc and phosphorylated glucocorticoid receptor This is a multi-center observational cohort study of patients with diabetic foot ulcers (DFU) to develop and validate potential tissue-based biomarkers that predict complete wound healing. Eligible and consented participants will begin standard of care treatment after collection of tissue specimens from the wound’s edge. An additional tissue specimen is collected at 4 weeks. Tissues will be tested for c-myc and phosphorylated glucocorticoid receptor (p-GR) levels using validated protocols at a central laboratory. Participants will be followed weekly for up to 12 weeks or until complete wound healing (whichever occurs first). One final assessment 2 weeks after complete wound healing will occur to confirm healing.

Contact Shannon Meyer smeyer27@stanford.edu with question about this trial.
DETECT The DETECT study’s purpose is to find a way to distinguish between type 2 diabetes and diabetes that are due to other pancreatic conditions, such as pancreatic cancer and pancreatitis. By enrolling patients with diabetes from different causes, this study will help us better understand how pancreatic disorders influence patients’ risk for diabetes and how we can identify and treat diabetes that occurs due to pancreatic disorders. Patients participating in the DETECT Study will be asked to complete one study visit, which will include a focused questionnaire and a 30-minute mixed meal test (the estimated length of the entire study visit is 1 hour). The mixed meal test includes collecting a total of 3 blood samples to measure changes in levels of proteins and chemicals following ingestion of a nutrient drink.

For more information, please contact:
Lorena Pineda
Email: ljpineda@stanford.edu
Phone : 650-725-2767
Metabolic Challenge for Personalized Diet Profiling The McLaughlin Lab is looking for pre-diabetic or non-diabetic volunteers between the ages of 35-65 for a study looking at how fat cells respond to changes in weight and diet. Eligible participants will receive screening for prediabetes/insulin resistance, evaluation of risk factors for heart disease, abdominal and liver fat measurements as well as personal counseling with a registered dietitian. This study is appropriate for individuals who are interested in learning more about their risk for metabolic disease, as well as personalized lifestyle approaches to decrease these risks. For more information please email Nicole Turk at nturk@stanford.edu or call (650) 888-0144.