Allan Reiss

Allan Reiss, MD, Howard C. Robbins Professor of Psychiatry and Behavioral Sciences, Radiology and Pediatrics; Director, Center for Interdisciplinary Brain Sciences Research, Stanford University School of Medicine.

 

Research Description: Dr. Reiss is a distinguished investigator in neuropsychiatry, genetics, neuroimaging, neurodevelopment, and cognitive neuroscience, who uses an interdisciplinary, multi-level scientific approach to elucidate neurobiological pathways that lead to both typical and atypical behavioral and cognitive outcomes in children and adolescents. He has led multiple longitudinal studies of early brain development in children with medical and genetic risk factors, or diseases like diabetes. His activities as a member of the Stanford DRC include work on the neurodevelopmental effects of early-onset diabetes in children. He has helped establish a multi-institution consortium (DirecNet) for these studies renowned for its cohesiveness, productivity and effectiveness. As director of the Center for Interdisciplinary Brain Sciences Research, he has introduced a wide-range of expertise in all aspects of multi-modal pediatric neuroimaging including subject preparation, scan acquisition and image analysis. His lab was one of the first to use neuroimaging to illuminate neural correlates of behavioral neurogenetic conditions. Studies of brain anatomy, white matter, function and neurometabolites have contributed significantly to our understanding of the brain as an intermediate phenotype that mediates the interaction of genetic risk and environment influences on cognitive-behavioral outcome. An important focus of this research has been on medical risk factors in childhood and adolescence, particularly childhood-onset Type 1 diabetes.

Selected relevant publications (Stanford DRC members in BOLD):

1.     Marzelli M, Mazaika P, Barnea-Goraly N, Hershey T, Tsalikian E, Tamborlane W, Mauras N, White N, Buckingham B, Beck R, Ruedy K, Kollman C, Cheng P, Reiss AL: Neuroanatomical correlates of dysglycemia in young children with type 1 diabetes mellitus. Diabetes 63(1):343-353, 2014.

 

2.     Mauras N, Mazaika P, Buckingham B, Weinzimer S, White N, Tsalikian E, Hershey T, Cato A, Cheng P, Kollman C, Beck R, Ruedy K, Aye T, Fox L, Arbelaez A, Wilson D, Tansey M, Tamborlane W, Peng D, Marzelli M, Winer K, Reiss AL: Longitudinal assessment of neuroanatomical and cognitive differences in young children with type 1 diabetes: Association with hyperglycemia. Diabetes 64(5):1770-1779, 2015.

 

3.     Mazaika P, Weinzimer S, Mauras N, Buckingham B, White N, Tsalikian E, Hershey E, Cato A, Aye T, Fox L, Wilson D, Tansey M, Tamborlane W, Peng D, Raman M, Marzelli M, Reiss AL: Variations in brain volume and growth in young children with type 1 diabetes. Diabetes 65(2):476-485, 2016.

 

4.     Saggar M, Tsalikian E, Mauras N, Mazaika P, White NH, Weinzimer S, Buckingham B, Hershey T, Reiss AL; Diabetes Research in Children Network: Compensatory hyper-connectivity in developing brains of young children with type 1 diabetes. Diabetes. 2016 Oct 4. [Epub ahead of print].

 

5.     Cato MA, Mauras N, Mazaika P, Kollman C, Cheng P, Aye T, Ambrosino J, Beck RW, Ruedy KJ, Reiss AL, Tansey M, White NH, Hershey T; Diabetes Research in Children Network. Longitudinal Evaluation of Cognitive Functioning in Young Children with Type 1 Diabetes over 18 Months. J Int Neuropsychol Soc. 2016 Mar;22(3):293-302.