Ananta Addala
Ananta Addala, DO, Assistant Professor, Department of Pediatrics, Division of Endocrinology, Stanford University School of Medicine
Research Description: Dr. Ananta Addala is a pediatric endocrinologist and physician scientist at Stanford University addressing disparities in pediatric type 1 diabetes management and outcomes. As a physician with a background in pediatric endocrinology, epidemiology, and behavioral health, she aims to build an evidence-based approach to addressing T1D disparities by systematically evaluating youth-, family-, provider-, and system-level barriers to optimal diabetes care in youth from low socioeconomic and racial/ethnic minority groups.
She is funded by NIDDK K23 to understand and address disparities in pediatric diabetes technology access and utilization. She also has funding from the Maternal Child Research Institute and Helmsley Charitable Trust. To date, her publications have demonstrated that the disparities in pediatric T1D by socioeconomic status are worsening in the US, provider bias against public insurance is common, and public insurance mediated interruptions to diabetes technology adversely impact glycemic outcomes. She has also been leading the efforts to improve justice, equity, diversity, and inclusion in research at Stanford University through her leadership at Stanford Pediatrics Advancing Anti-Racism Coalition and as the co-chair of TrialNet's Underrepresented Minorities Outreach Committee.
Selected relevant publications (Stanford DRC members are in BOLD, note #5 is an abstract with a manuscript under review)
Addala A, Hanes S, Naranjo D, Maahs DM, Hood KK. Provider Implicit Bias Impacts Pediatric Type 1 Diabetes Technology Recommendations in the United States: Findings from The Gatekeeper Study. J Diabetes Sci Technol. 2021 Apr 15:19322968211006476. doi: 10.1177/19322968211006476. Epub ahead of print. PMID: 33858206.
Addala A, Maahs DM, Scheinker D, Chertow S, Leverenz B, Prahalad P. Uninterrupted Continuous Glucose Monitoring Access is Associated with a Decrease in HbA1c in Youth with Type 1 Diabetes and Public Insurance. Pediatr Diabetes. 2020 Jul 17. PMID: 32681582.
Addala A, Chan RY, Vargas J, Weigensberg MJ. Global Well-Being is Associated with A1c and Frequency of Self-Monitoring of Blood Glucose in Predominantly Latinx Youth and Young Adults with Type 1 Diabetes. Diabetes Spectrum. December 21, 2020. doi: 10.2337/ds20-0041.
Addala A, Roque X, Figg L, Anez-Zabala C, Clark C, Lal RA, Haller MJ, Maahs DM, Walker, AF; 262-OR: Recruiting Historically Underrepresented Individuals into Clinical Trials: Key Lessons from Project ECHO Diabetes. Diabetes 1 June 2022; 71 (Supplement_1): 262–OR. https://doi.org/10.2337/db22-262-OR.
Hughes MS, Addala A, Buckingham B. Digital Technology for Diabetes. N Engl J Med. 2023 Nov 30;389(22):2076-2086. doi: 10.1056/NEJMra2215899. PMID: 38048189; PMCID: PMC12333919.
Leadley C, Addala A, Berkeley J, Crocket H, Davis EA, Hewapathirana N, Hussain S, Lal R, Lomax K, Wilkinson T, de Bock M, Burckhardt MA. Following in Banting's footsteps or straying from the path? Observations from contemporary diabetes innovation. Front Endocrinol (Lausanne). 2023 Nov 14;14:1270517. doi: 10.3389/fendo.2023.1270517. PMID: 38033993; PMCID: PMC10686253.
Figg L, Addala A, Jain I, Anez C, Midney P, DeChirico C, Symanski C, Fitzgerald BC, Colbert K, Raymer T, Stockton-Joreteg C, Murphy E, Collins L, Bernstein C, Hechavarria M, Sheehan EP, Bernier A, Westen SC, Hood KK, Zaharieva DP, Basina M, Cuttriss N, Filipp SL, Gurka MJ, Walker AF, Maahs DM, Haller MJ, Lal RA. The Promising Success of Project Extension for Community Healthcare Outcomes (ECHO) Diabetes: Case Series. JMIR Diabetes. 2023 Aug 3;8:e46050. doi: 10.2196/46050. PMID: 37535407; PMCID: PMC10436109.
Lewit EM, Figg LE, Addala A, Filipp SL, Lal R, Gurka MJ, Herndon JB, Haller MJ, Maahs DM, Walker AF; Project ECHO Diabetes Research Team. Project ECHO Diabetes Cost Modeling to Support the Replication and Expansion of Tele-mentoring Programs in Non-research Settings. Diabetes Ther. 2023 Mar;14(3):509-518. doi: 10.1007/s13300-022-01364-3. Epub 2023 Jan 21. PMID: 36680682; PMCID: PMC9981830.
Addala A, Hechavarria M, Figg L, Roque X, Filipp SL, Anez-Zabala C, Lal R, Gurka MJ, Haller MJ, Maahs DM, Walker AF. Recruiting historically under-represented individuals into Project ECHO Diabetes: using barrier analysis to understand disparities in clinical research in the USA. BMJ Open. 2023 Aug 30;13(8):e072546. doi: 10.1136/bmjopen-2023-072546. PMID: 37648378; PMCID: PMC10471869.
Corbin KD, Igudesman D, Addala A, Casu A, Crandell J, Kosorok MR, Maahs DM, Pokaprakarn T, Pratley RE, Souris KJ, Thomas JM, Zaharieva DP, Mayer-Davis EJ; ACT1ON Consortium. Design of the Advancing Care for Type 1 Diabetes and Obesity Network energy metabolism and sequential multiple assignment randomized trial nutrition pilot studies: An integrated approach to develop weight management solutions for individuals with type 1 diabetes. Contemp Clin Trials. 2022 Jun;117:106765. doi: 10.1016/j.cct.2022.106765. Epub 2022 Apr 20. PMID: 35460915; PMCID: PMC9164141.
Zaharieva DP, Addala A, Prahalad P, Leverenz B, Arrizon-Ruiz N, Ding VY, Desai M, Karger AB, Maahs DM. An Evaluation of Point-of-Care HbA1c, HbA1c Home Kits, and Glucose Management Indicator: Potential Solutions for Telehealth Glycemic Assessments. Diabetology (Basel). 2022 Sep;3(3):494-501. doi: 10.3390/diabetology3030037. Epub 2022 Sep 13. PMID: 37163187; PMCID: PMC10166120.
Addala A, Auzanneau M, Miller K, Maier W, Foster N, Kapellen T, Walker A, Rosenbauer J, Maahs DM, Holl RW. A Decade of Disparities in Diabetes Technology Use and HbA1c in Pediatric Type 1 Diabetes: A Transatlantic Comparison. Diabetes Care. 2021 Jan;44(1):133-140. doi: 10.2337/dc20-0257. Epub 2020 Sep 16. PMID: 32938745; PMCID: PMC8162452.
Prahalad P, Ding VY, Zaharieva DP, Addala A, Johari R, Scheinker D, Desai M, Hood K, Maahs DM. Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Type 1 Diabetes: Pilot 4T Study. J Clin Endocrinol Metab. 2021 Nov 28:dgab859. doi: 10.1210/clinem/dgab859. Epub ahead of print. PMID: 34850024.
Addala A, Zaharieva DP, Gu AJ, Prahalad P, Scheinker D, Buckingham B, Hood KK, Maahs DM. Clinically Serious Hypoglycemia Is Rare and Not Associated With Time-in-range in Youth With New-onset Type 1 Diabetes. J Clin Endocrinol Metab. 2021 Oct 21;106(11):3239-3247. doi: 10.1210/clinem/dgab522. PMID: 34265059; PMCID: PMC8530719.
Tanenbaum ML, Zaharieva DP, Addala A, Ngo J, Prahalad P, Leverenz B, New C, Maahs DM, Hood KK. 'I was ready for it at the beginning': Parent experiences with early introduction of continuous glucose monitoring following their child's Type 1 diabetes diagnosis. Diabet Med. 2021 Aug;38(8):e14567. PMID: 33772862.
Tanenbaum ML, Zaharieva DP, Addala A, Prahalad P, Hooper JA, Leverenz B, Cortes AL, Arrizon-Ruiz N, Pang E, Bishop F, Maahs DM. 'Much more convenient, just as effective': Experiences of starting continuous glucose monitoring remotely following Type 1 diabetes diagnosis. Diabet Med. 2022 Jul 28:e14923. PMID: 35899591.
Addala A, Ding V, Zaharieva DP, Bishop FK, Adams AS, King AC, Johari R, Scheinker D, Hood KK, Desai M, Maahs DM, Prahalad P; Teamwork, Targets, Technology, and Tight Control (4T) Study Group. Disparities in Hemoglobin A1c Levels in the First Year After Diagnosis Among Youths With Type 1 Diabetes Offered Continuous Glucose Monitoring. JAMA Netw Open. 2023 Apr 3;6(4):e238881. doi: 10.1001/jamanetworkopen.2023.8881. PMID: 37074715; PMCID: PMC10116368.
Tanenbaum ML, Addala A, Hanes S, Ritter V, Bishop FK, Cortes AL, Pang E, Hood KK, Maahs DM, Zaharieva DP; 4T Study Group. "It changed everything we do": A mixed methods study of youth and parent experiences with a pilot exercise education intervention following new diagnosis of type 1 diabetes. J Diabetes Complications. 2024 Jan;38(1):108651. doi: 10.1016/j.jdiacomp.2023.108651. Epub 2023 Nov 24. PMID: 38043358; PMCID: PMC10843536.
Wang CJ, Lewit EM, Clark CL, Lee FW, Maahs DM, Haller MJ, Addala A, Lal RA, Cuttriss N, Baer LG, Figg LE, Añez-Zabala C, Sheehan EP, Westen SC, Bernier AV, Donahoo WT, Walker AF. Multisite Quality Improvement Program Within the Project ECHO Diabetes Remote Network. Jt Comm J Qual Patient Saf. 2024 Jan;50(1):66-74. doi: 10.1016/j.jcjq.2023.08.001. Epub 2023 Aug 12. PMID: 37718146.
Zaharieva DP, Ding VY, Addala A, Prahalad P, Bishop F, Hood KK, Desai M, Wilson DM, Buckingham BA, Maahs DM. Diabetic Ketoacidosis at Diagnosis in Youth with Type 1 Diabetes Is Associated with a Higher Hemoglobin A1c Even with Intensive Insulin Management. Diabetes Technol Ther. 2024 Mar;26(3):176-183. doi: 10.1089/dia.2023.0405. PMID: 37955644; PMCID: PMC10877392.
Prahalad P, Scheinker D, Desai M, Ding VY, Bishop FK, Lee MY, Ferstad J, Zaharieva DP, Addala A, Johari R, Hood K, Maahs DM. Equitable implementation of a precision digital health program for glucose management in individuals with newly diagnosed type 1 diabetes. Nat Med. 2024 Jul;30(7):2067-2075. doi: 10.1038/s41591-024-02975-y. Epub 2024 May 3. PMID: 38702523; PMCID: PMC11847559.
Tanenbaum ML, Pang E, Tam R, Bishop FK, Prahalad P, Zaharieva DP, Addala A, Wong JJ, Naranjo D, Hood KK, Maahs DM. 'We're taught green is good': Perspectives on time in range and time in tight range from youth with type 1 diabetes, and parents of youth with type 1 diabetes. Diabet Med. 2024 Dec;41(12):e15423. doi: 10.1111/dme.15423. Epub 2024 Aug 8. PMID: 39118381; PMCID: PMC11560526.
Walker AF, Haller MJ, Addala A, Filipp SL, Lal R, Gurka MJ, Figg LE, Hechavarria M, Zaharieva DP, Malden KG, Hood KK, Westen SC, Wong JJ, Donahoo WT, Basina M, Bernier AV, Duncan P, Maahs DM. Not all healthcare inequities in diabetes are equal: a comparison of two medically underserved cohorts. BMJ Open Diabetes Res Care. 2024 Sep 5;12(4):e004229. doi: 10.1136/bmjdrc-2024-004229. PMID: 39242122; PMCID: PMC11381725.
Addala A, Ritter V, Schneider-Utaka AK, Alamarie SA, Pang E, Balistreri I, Shaw B, Bishop FK, Zaharieva DP, Prahalad P, Desai M, Maahs DM, Hood KK; 4T Team. Psychosocial outcomes in a diverse sample of youth and their families who initiated continuous glucose monitoring within the first year of type 1 diabetes diagnosis. Diabetes Obes Metab. 2025 Feb;27(2):933-943. doi: 10.1111/dom.16093. Epub 2024 Nov 27. PMID: 39604317; PMCID: PMC11700754.
Walker AF, Haller MJ, Addala A, Filipp SL, Lal RA, Gurka MJ, Figg LE, Hechavarria M, Zaharieva DP, Malden KG, Hood KK, Westen SC, Wong JJ, Donahoo WT, Basina M, Bernier AV, Maahs DM; ECHO Diabetes Study Team. Project ECHO Diabetes Trial Improves Outcomes for Medically Underserved People. Diabetes Care. 2025 Feb 1;48(2):243-250. doi: 10.2337/dc24-2100. PMID: 39688288; PMCID: PMC11770159.