Andrew Hoffman

Andrew R. Hoffman, MD, Professor, Department of Medicine, Division of Endocrinology, Metabolism and Gerontology, Stanford University School of Medicine

Research Description: Dr. Hoffman’s research focuses on examining epigenetic mechanisms of gene expression and on studying the role of insulin-like growth factors (IGF) and growth hormone in normal physiology, in metabolic derangements and in cancer development. His studies have implications for the therapeutic use of growth hormone and IGF in development and in the clinical consequences of aging. He is currently studying the natural history of bone health in elderly men and neuroendocrine function in aging and traumatic brain injury. Dr. Hoffman is the PI on the NIH T32 Training Grant “Diabetes, Endocrinology, and Metabolism”, now in its 46th consecutive year of funding.

Selected relevant publications (Stanford DRC Members in BOLD):

  1. Laddu DR, Parimi N, Stone KL, Lapidus J, Hoffman AR, Stefanick ML, Langsetmo L. Physical Activity Trajectories and Associated Changes in Physical Performance in Older Men: The MrOS Study. J Gerontol A Biol Sci Med Sci. 2020 Sep 25;75(10):1967-1973. PMID: 32232383; PMCID: PMC7518557. 

  2. Schousboe JT, Kats AM, Langsetmo L, Vo TN, Taylor BC, Schwartz AV, Cawthon PM, Lewis CE, Barrett-Connor E, Hoffman AR, Orwoll ES, Ensrud KE; Osteoporotic Fractures in Men (MrOS) Study Research Group. Central Obesity and Visceral Adipose Tissue Are Not Associated With Incident Atherosclerotic Cardiovascular Disease Events in Older Men. J Am Heart Assoc. 2018 Aug 21;7(16):e009172. PMID: 30369326; PMCID: PMC6201395. 

  3. Napoli N, Schwartz AV, Schafer AL, Vittinghoff E, Cawthon PM, Parimi N, Orwoll E, Strotmeyer ES, Hoffman AR, Barrett-Connor E, Black DM; Osteoporotic Fractures in Men (MrOS) Study Research Group. Vertebral Fracture Risk in Diabetic Elderly Men: The MrOS Study. J Bone Miner Res. 2018 Jan;33(1):63-69. PMID: 28861910; PMCID: PMC6702944.