Eric Gross

Eric R. Gross, MD, PhD, Assistant Professor, Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine

Research Description: Dr. Gross’s laboratory focuses on mitochondrial function in the context of cardiovascular disease. They are studying the role for an ion channel, transient receptor potential vanilloid 1 (TRPV1) at the mitochondria in the cardiovascular system, with a focus on cardiac myocytes and endothelial cells. The study of TRPV1 in endothelial cells is a new direction for his lab which has tremendous potential to unlock the cellular mechanisms of endothelial cell dysfunction caused by diabetes mellitus and provide treatment strategies. In support of this work, he was the recipient of a 2017 P&F award jointly administered by the Stanford Cardiovascular Institute and SDRC.

Selected relevant publications (Stanford DRC Members in BOLD):

  1. Otto M, Bucher C, Liu W, Müller M, Schmidt T, Kardell M, Driessen MN, Rossaint J, Gross ER, Wagner NM. 12(S)-HETE mediates diabetes-induced endothelial dysfunction by activating intracellular endothelial cell TRPV1. J Clin Invest. 2020 Sep 1;130(9):4999-5010. doi: 10.1172/JCI136621. PMID: 32584793; PMCID: PMC7456227. 

  2. Chen CH, Ferreira JCB, Mochly-Rosen D, Gross ER. Alcohol consumption and vascular disease: other points to consider. Lancet. 2019 Nov 2;394(10209):1617-1618. doi: 10.1016/S0140-6736(19)31880-X. PMID: 31690444; PMCID: PMC7259464. 

  3. Ferreira JCB, Mori MA, Gross ER. Mitochondrial Bioenergetics and Quality Control Mechanisms in Health and Disease. Oxid Med Cell Longev. 2019 Jan 20;2019:5406751. doi: 10.1155/2019/5406751. PMID: 30805083; PMCID: PMC6360560.