Joy Wu

Joy Y. Wu, MD, PhD, Associate Professor, Department of Medicine, Division of Endocrinology, Gerontology and Metabolism; Vice Chair, Basic Science, Department of Medicine; Co-Director, Translational Investigator Program; Stanford University School of Medicine 

Research Description: Dr. Wu’s research has made important contributions to our understanding of parathyroid hormone signaling pathways in bone forming osteoblasts and their roles in mesenchymal lineage commitment to bone and fat. She has developed methods to investigate the interactions between osteoblast differentiation, marrow fat accumulation, and bone marrow hematopoiesis. This includes studies in subjects with diabetes.

Selected relevant publications (Stanford DRC Members in BOLD):

  1. Valderrábano RJ, Buzkova P, Chang PY, Zakai NA, Fink HA, Robbins JA, Lee JS, Wu JY; Cardiovascular Health Study group. Association of bone mineral density with hemoglobin and change in hemoglobin among older men and women: The Cardiovascular Health Study. Bone. 2019 Mar;120:321-326. doi: 10.1016/j.bone.2018.11.010. PMID: 30448304; PMCID: PMC6360112. 

  2. Valderrábano RJ, Wu JY. Bone and blood interactions in human health and disease. Bone. 2019 Feb;119:65-70. doi: 10.1016/j.bone.2018.02.019. PMID: 29476979. 

  3. Tan SH, Chubb R, Oh J, Riley AK, Kimura T, Wu SM, Wu JY. In Vivo Rescue of the Hematopoietic Niche by Pluripotent Stem Cell Complementation of Defective Osteoblast Compartments. Stem Cells. 2017 Oct;35(10):2150-2159. doi: 10.1002/stem.2670. PMID: 28741855; PMCID: PMC5610643.