Latha Palaniappan

Latha Palaniappan, MD, MS, Clinical Professor, Department of Medicine, Division of Cardiovascular Medicine and Professor (by Courtesy), Department of Epidemiology and Population Health, Stanford University School of Medicine

Research Description: For the past fifteen years Dr. Palaniappan has been engaged in patient-oriented research in the areas of diabetes and cardiovascular risk. Her research is aimed at addressing the gap in knowledge of health-related and patient-centered outcomes, specifically exploring prevention and treatment approaches and gender and racial/ethnic disparities in obesity, insulin resistance, type 2 diabetes mellitus (T2DM) and coronary heart disease. As lifestyle and contextual factors greatly impact cardiovascular disease risk factors, her research focuses on qualitative and quantitative approaches to develop culturally aware treatments and recommendations that health care organizations and physicians can carry into their practice. Current studies include examining the clinical effectiveness of structured physical activity programs for T2DM management.

Selected relevant publications (Stanford DRC members in BOLD):

  1. Kobayashi Y, Christle JW, Contrepois K, Nishi T, Moneghetti K, Cauwenberghs N, Myers J, Kuznetsova T, Palaniappan L, Haddad F. Peripheral Oxygen Extraction and Exercise Limitation in Asymptomatic Patients with Diabetes Mellitus. Am J Cardiol. 2021 Mar 20:S0002-9149(21)00252-6. doi: 10.1016/j.amjcard.2021.03.011. PMID: 33757787. 

  2. Ward A, Sarraju A, Chung S, Li J, Harrington R, Heidenreich P, Palaniappan L, Scheinker D, Rodriguez F. Machine learning and atherosclerotic cardiovascular disease risk prediction in a multi-ethnic population. NPJ Digit Med. 2020 Sep 23;3:125. doi: 10.1038/s41746-020-00331-1. PMID: 33043149; PMCID: PMC7511400. 

  3. Nishi T, Kobayashi Y, Christle JW, Cauwenberghs N, Boralkar K, Moneghetti K, Amsallem M, Hedman K, Contrepois K, Myers J, Mahaffey KW, Schnittger I, Kuznetsova T, Palaniappan L, Haddad F. Incremental value of diastolic stress test in identifying subclinical heart failure in patients with diabetes mellitus. Eur Heart J Cardiovasc Imaging. 2020 Aug 1;21(8):876-884. doi: 10.1093/ehjci/jeaa070. PMID: 32386203; PMCID: PMC7369686. 

  4. Faroqi L, Wong M, Bonde S, Wong CW, Walai K, West W, Goni DT, Araya S, Azamey S, Nacif-Coelho C, Raghuram SS, Vera K, Mittal A, Groppo L, Christensen M, Johannsen N, Haddad F, Moharir M, Palaniappan L. Evaluating the clinical implementation of structured exercise: A randomized controlled trial among non-insulin dependent type II diabetics. Contemp Clin Trials. 2018 Nov;74:25-31. doi: 10.1016/j.cct.2018.09.003. PMID: 30205182. 

  5. Mukherji AB, Idowu V, Zhao L, Leung LLK, Shen S, Palaniappan L, Morser J. Chemerin Levels in Individuals with Type 2 Diabetes and a Normal Weight versus Individuals with Type 2 Diabetes and Obesity: An Observational, Cross-Sectional Study. Biomedicines. 2024 Apr 30;12(5):983. doi: 10.3390/biomedicines12050983. PMID: 38790945; PMCID: PMC11117893. 

  6. Mukherji AB, Lu D, Qin F, Hedlin H, Johannsen NM, Chung S, Kobayashi Y, Haddad F, Lamendola C, Basina M, Talamoa R, Myers J, Palaniappan L. Effectiveness of a Community-Based Structured Physical Activity Program for Adults With Type 2 Diabetes: A Randomized Clinical Trial. JAMA Netw Open. 2022 Dec 1;5(12):e2247858. PMID: 36542382. 

  7. Kobayashi Y, Nishi T, Christle JW, Cauwenberghs N, Kuznetsova T, Palaniappan L, Haddad F. Epicardial fat and Stage B heart failure among overweight/obese and normal weight individuals with diabetes mellitus. Int J Cardiovasc Imaging. 2023 Dec;39(12):2451-2461. doi: 10.1007/s10554-023-02944-5. Epub 2023 Sep 11. PMID: 37695438; PMCID: PMC11088949. 

  8. Mukherji AB, Idowu V, Zhao L, Leung LLK, Shen S, Palaniappan L, Morser J. Chemerin Levels in Individuals with Type 2 Diabetes and a Normal Weight versus Individuals with Type 2 Diabetes and Obesity: An Observational, Cross-Sectional Study. Biomedicines. 2024 Apr 30;12(5):983. doi: 10.3390/biomedicines12050983. PMID: 38790945; PMCID: PMC11117893.