Marina Basina

Marina Basina, MD, Clinical Professor, Department of Medicine, Division of Endocrinology, Gerontology, and Metabolism, Stanford University School of Medicine 

Research Description: Dr. Basina is a clinical endocrinologist and clinical researcher with a focus on diabetes management. She is actively involved in the Stanford diabetes research community in multiple ways as described below. Dr. Basina was a co-investigator on an NIH-sponsored research study of Safety and Efficacy of Sensor- Augmented Continuous Subcutaneous Insulin Infusion in Patients with Diabetic Gastroparesis. Dr. Basina has served as a Stanford site primary investigator of a Sanofi sponsored multi-center research study comparing two different insulins for diabetes control and the incidence of hypoglycemia in patients undergoing hemodialysis with diabetes-related End Stage Renal disease. She also served as a PI on a Novo Nordisk sponsored multicenter randomized controlled trial comparing two basal insulins (Lantus and Degludec) for type 2 diabetes (NN1250-4252 - Site 164). 

She has previously collaborated with other SDRC members (Abbasi, McLaughlin, Reaven*) in published studies of insulin resistance, dietary interventions and diabetes-associated cardiovascular disease risk. Dr Basina is a co-investigator on Expansion and Evaluation of ECHO (Extension for Community Healthcare Outcomes) for diabetics on Intensive Insulin Therapy. The overall goal of this study, funded by Helmsley Foundation, Inc., is to build an innovative healthcare delivery model to effectively manage underserved patients with type 1 Diabetes who do not receive routine specialty care. She is also a co-investigator of a working group in the NCI/NIDDK funded multi-center consortium (CPDPC) that is actively involved in recruiting pancreatitis patients in order to understand progression from recurrent acute to chronic pancreatitis 

In addition, Dr. Basina is a co-leader with Dr. Justin Annes of Enrichment activities in SDRC, with a focus on community outreach efforts (detailed in the Enrichment section of this proposal). Finally, Dr. Basina will focus on clinical care of subjects undergoing islet auto-transplantation in the SPIRIT program developed by several SDRC members, including Drs. Kraemer, S.K. Kim, Maahs, Meyer, Park, Thakor and Visser. 

Selected relevant publications (Stanford DRC Members in BOLD):

  1. Erkers T, Xie BJ, Kenyon LJ, Smith B, Rieck M, Jensen KP, Ji X, Basina M, Strober S, Negrin RS, Maecker HT, Meyer EH. High-parametric evaluation of human invariant natural killer T cells to delineate heterogeneity in allo- and autoimmunity. Blood. 2020 Mar 12;135(11):814-825. doi: 10.1182/blood.2019001903. PMID: 31935280; PMCID: PMC7068034. 

  2. Lal RA, Basina M, Maahs DM, Hood K, Buckingham B, Wilson DM. One Year Clinical Experience of the First Commercial Hybrid Closed-Loop System. Diabetes Care. 2019 Dec;42(12):2190-2196. doi: 10.2337/dc19-0855. PMID: 31548247; PMCID: PMC6868462. 

  3. Lal RA, Cuttriss N, Haller MJ, Yabut K, Anez-Zabala C, Hood KK, Sheehan E, Basina M, Bernier A, Baer LG, Filipp SL, Wang CJ, Town MA, Gurka MJ, Maahs DM, Walker AF. Primary Care Providers in California and Florida Report Low Confidence in Providing Type 1 Diabetes Care. Clin Diabetes. 2020 Apr;38(2):159-165. doi: 10.2337/cd19-0060. PMID: 32327888; PMCID: PMC7164993. 

  4. Dow ER, Khan NC, Chen KM, Mishra K, Perera C, Narala R, Basina M, Dang J, Kim M, Levine M, Phadke A, Tan M, Weng K, Do DV, Moshfeghi DM, Mahajan VB, Mruthyunjaya P, Leng T, Myung D. AI-Human Hybrid Workflow Enhances Teleophthalmology for the Detection of Diabetic Retinopathy. Ophthalmol Sci. 2023 May 12;3(4):100330. doi: 10.1016/j.xops.2023.100330. PMID: 37449051; PMCID: PMC10336195. 

  5. Figg L, Addala A, Jain I, Anez C, Midney P, DeChirico C, Symanski C, Fitzgerald BC, Colbert K, Raymer T, Stockton-Joreteg C, Murphy E, Collins L, Bernstein C, Hechavarria M, Sheehan EP, Bernier A, Westen SC, Hood KK, Zaharieva DP, Basina M, Cuttriss N, Filipp SL, Gurka MJ, Walker AF, Maahs DM, Haller MJ, Lal RA. The Promising Success of Project Extension for Community Healthcare Outcomes (ECHO) Diabetes: Case Series. JMIR Diabetes. 2023 Aug 3;8:e46050. doi: 10.2196/46050. PMID: 37535407; PMCID: PMC10436109. 

  6. Forlenza GP, Vigers T, Berget C, Messer LH, Lal RA, Basina M, Maahs DM, Hood K, Buckingham B, Wilson DM, Wadwa RP, Driscoll KA, Pyle L. Predicting Success with a First-Generation Hybrid Closed-Loop Artificial Pancreas System Among Children, Adolescents, and Young Adults with Type 1 Diabetes: A Model Development and Validation Study. Diabetes Technol Ther. 2022 Mar;24(3):157-166. doi: 10.1089/dia.2021.0326. Epub 2021 Dec 1. PMID: 34780306; PMCID: PMC8971998. 

  7. Tanenbaum ML, Messer LH, Wu CA, Basina M, Buckingham BA, Hessler D, Mulvaney SA, Maahs DM, Hood KK. Help when you need it: Perspectives of adults with T1D on the support and training they would have wanted when starting CGM. Diabetes Res Clin Pract. 2021 Oct;180:109048. doi: 10.1016/j.diabres.2021.109048. Epub 2021 Sep 14. PMID: 34534592; PMCID: PMC8578423. 

  8. Hsu L, Buckingham B, Basina M, Ekhlaspour L, von Eyben R, Wang J, Lal RA. Fast-Acting Insulin Aspart Use with the MiniMedTM 670G System. Diabetes Technol Ther. 2021 Jan;23(1):1-7. doi: 10.1089/dia.2020.0083. PMID: 32520594; PMCID: PMC7864093. 

  9. Tanenbaum ML, Ngo J, Hanes SJ, Basina M, Buckingham BA, Hessler D, Maahs DM, Mulvaney S, Hood KK. ONBOARD: A Feasibility Study of a Telehealth-Based Continuous Glucose Monitoring Adoption Intervention for Adults with Type 1 Diabetes. Diabetes Technol Ther. 2021 Dec;23(12):818-827. PMID: 34270351. 

  10. Mukherji AB, Lu D, Qin F, Hedlin H, Johannsen NM, Chung S, Kobayashi Y, Haddad F, Lamendola C, Basina M, Talamoa R, Myers J, Palaniappan L. Effectiveness of a Community-Based Structured Physical Activity Program for Adults With Type 2 Diabetes: A Randomized Clinical Trial. JAMA Netw Open. 2022 Dec 1;5(12):e2247858. PMID: 36542382. 

  11. Davis GM, Hughes MS, Brown SA, Sibayan J, Perez-Guzman MC, Stumpf M, Thompson Z, Basina M, Patel RM, Hester J, Abraham A, Ly TT, Chaney C, Tan M, Hsu L, Kollman C, Beck RW, Lal R, Buckingham B, Pasquel FJ. Automated Insulin Delivery with Remote Real-Time Continuous Glucose Monitoring for Hospitalized Patients with Diabetes: A Multicenter, Single-Arm, Feasibility Trial. Diabetes Technol Ther. 2023 Aug 28. PMID: 37578778; PMCID: PMC10611957. 

  12. Wu X, Chen PI, Whitener RL, MacDougall MS, Coykendall VMN, Yan H, Kim YB, Harper W, Pathak S, Iliopoulou BP, Hestor A, Saunders DC, Spears E, Sévigny J, Maahs DM, Basina M, Sharp SA, Gloyn AL, Powers AC, Kim SK, Jensen KP, Meyer EH. CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets. Front Immunol. 2024 Jun 28;15:1415102. doi: 10.3389/fimmu.2024.1415102. PMID: 39007132; PMCID: PMC11239501. 

  13. Walker AF, Haller MJ, Addala A, Filipp SL, Lal R, Gurka MJ, Figg LE, Hechavarria M, Zaharieva DP, Malden KG, Hood KK, Westen SC, Wong JJ, Donahoo WT, Basina M, Bernier AV, Duncan P, Maahs DM. Not all healthcare inequities in diabetes are equal: a comparison of two medically underserved cohorts. BMJ Open Diabetes Res Care. 2024 Sep 5;12(4):e004229. doi: 10.1136/bmjdrc-2024-004229. PMID: 39242122; PMCID: PMC11381725. 

  14. Lee MY, Seav SM, Ongwela L, Lee JJ, Aubyrn R, Cao FY, Kalinsky A, Aparicio Ramos O, Gu Y, Kingston K, Ivanovic M, Buckingham BA, Desai D, Lal RA, Tan M, Basina M, Hughes MS. Empowering Hospitalized Patients With Diabetes: Implementation of a Hospital-wide CGM Policy With EHR-Integrated Validation for Dosing Insulin. Diabetes Care. 2024 Oct 1;47(10):1838-1845. doi: 10.2337/dc24-0626. PMID: 39140891; PMCID: PMC11417271. 

  15. Walker AF, Haller MJ, Addala A, Filipp SL, Lal RA, Gurka MJ, Figg LE, Hechavarria M, Zaharieva DP, Malden KG, Hood KK, Westen SC, Wong JJ, Donahoo WT, Basina M, Bernier AV, Maahs DM; ECHO Diabetes Study Team. Project ECHO Diabetes Trial Improves Outcomes for Medically Underserved People. Diabetes Care. 2025 Feb 1;48(2):243-250. doi: 10.2337/dc24-2100. PMID: 39688288; PMCID: PMC11770159.