Mark Hlatky

Mark A. Hlatky, MD, Professor, Department of Medicine, Division of Primary Care and Outcomes Research and Division of Cardiovascular Medicine; Professor (By courtesy), Department of Epidemiology and Population Health, Stanford University School of Medicine

Research Description: Dr. Hlatky has a long-standing interest in the relationship between diabetes and cardiovascular disease, and has worked with both clinical databases and randomized clinical trials to investigate these associations. In particular, his leadership of a collaborative data analysis of 10 randomized trials confirmed the importance of diabetes as a significant modifier of the effectiveness of coronary revascularization, and the particular benefit of coronary bypass surgery for patients with diabetes and multi- vessel coronary disease. He was a member of the steering committee of the BARI 2D trial, testing alternative strategies to manage diabetes and coronary disease in patients with both disorders. He also has experience with establishing and analyzing clinical databases, and in the design and conduct of clinical research studies.

Selected relevant publications (Stanford DRC Members in BOLD):

  1. Søndergaard MM, Hlatky MA, Stefanick ML, Vittinghoff E, Nah G, Allison M, Gemmill A, Van Horn L, Park K, Salmoirago-Blotcher E, Sattari M, Sealy-Jefferson S, Shadyab AH, Valdiviezo C, Manson JE, Parikh NI. Association of Adverse Pregnancy Outcomes With Risk of Atherosclerotic Cardiovascular Disease in Postmenopausal Women. JAMA Cardiol. 2020 Sep 16;5(12):1390–8. PMID: 32936228; PMCID: PMC7495331. 

  2. Rezende PC, Hlatky MA, Hueb W, Garcia RMR, da Silva Selistre L, Lima EG, Garzillo CL, Scudeler TL, Boros GAB, Ribas FF, Serrano CV Jr, Ramires JAF, Kalil Filho R. Association of Longitudinal Values of Glycated Hemoglobin With Cardiovascular Events in Patients With Type 2 Diabetes and Multivessel Coronary Artery Disease. JAMA Netw Open. 2020 Jan 3;3(1):e1919666. PMID: 31968117; PMCID: PMC6991270. 

  3. Pallisgaard JL, Brooks MM, Chaitman B, Boothroyd DB, Perez M, Hlatky MA. Thiazolidinediones and risk of atrial fibrillation among patients with diabetes mellitus and coronary disease. Am J Med 2018;131:805-812; PMID: 29581079; PMCID: PMC7250530.

  4. Rezende PC, Everett BM, Brooks MM, Vlachos H, Orchard TJ, Frye RL, Bhatt DL, Hlatky MA. Hypoglycemia and Elevated Troponin in Patients With Diabetes and Coronary Artery Disease. J Am Coll Cardiol. 2018 Oct 9;72(15):1778-1786. PMID: 30286920.