Alpha cells can convert to insulin-producing beta cells in mice when just two genes are blocked, a new Stanford study shows. A similar mechanism may occur in people with diabetes.
Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health (NIH) to create the world's first, integrated knowledgebase of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.