Frederic Kraemer, MD

Professor of the Division of Endocrinology, Gerontology, and Metabolism
fbk@stanford.edu

 

Anna L Gloyn, DPhil

Co-director for the Pilot and Feasibility Program; Professor of Pediatrics (Endocrinology) and of Genetics agloyn@stanford.edu

SDRC PILOT AND FEASIBILITY AWARD PROGRAM

past Program Directors

2016-2023

Fredric B. Kraemer, M.D. received his Bachelor's degree in Chemistry from Emory University in 1970 and his M.D. from New York University in 1974. He was a house officer in Internal Medicine at Kings County/Downstate Medical Center (1974-1978) and a postdoctoral fellow in Endocrinology at Stanford University (1978-1982). He joined the faculty in the Department of Medicine at Stanford in 1983, with an appointment at the Palo Alto VA Hospital in 1988. Dr. Kraemer currently holds the Stanford University Professorship in Endocrinology and served as the Chief of the Division of Endocrinology, Gerontology and Metabolism through 2021. He is also a staff physician at the VA Palo Alto Health Care System. He was Associate Chief of Staff for Research and Development at the VA Palo Alto Health Care System from 2002-2007. His clinical and research interests have been focused on diabetes and cellular lipid metabolism. Dr. Kraemer's research program has been supported throughout his career by grants from the NIH and the Department of Veterans Affairs. He has won several awards including a Special Emphasis Research Career Award from the NIH, a SmithKline Beecham Junior Faculty Award in Diabetes, and an Arteriosclerosis Special Recognition Award from the Council on Arteriosclerosis, Thrombosis and Vascular Biology of the American Heart Association. Dr. Kraemer has served as president of the Western States Affiliate of the American Hearth Association, on the Scientific Advisory Committee of the University of California Tobacco-Related Disease Program, and the University of Minnesota Obesity Center, and the Advisory Board of the Deuel Conference on Lipids. In addition, he has served on a number of grant review boards for VA, NIH, American Diabetes Association and American Heart Association.

 

2023-2026

Dr. Anna Gloyn uses human genetics as a tool to understand cellular and molecular mechanisms for pancreatic beta cell failure in diabetes and related conditions. Her lab employs several different approaches, including genomics, in vitro human cell models and integrative physiology which are used to study both monogenic forms of diabetes due to rare mutations which are causal for disease through to common variants present in most of the population which increase an individual’s risk for developing diabetes.

She plays leading roles in multiple consortia for genetic discovery efforts for Type 2 diabetes and related glycaemic traits including the NIDDK funded Accelerated Medicines Partnership for common metabolic disease (AMP-CMD). She is co-lead for the International Common Disease Alliance (ICDA) Flagship Disease (Diabetes) and a member of both the Mechanisms and Medicines working groups and on the executive committee of the Atlas of Variant Effects (AVE) Alliance.  

She generates genetic data for the NIDDK funded Human Pancreas Atlas Project – Type 2 Diabetes (HPAP-T2D) and since 2020 the Integrated Islet Distribution Program (IIDP) where she heads up the Human Islet Genetic Initiative (HIGI).  Dr Gloyn has a long-term collaboration with Patrick MacDonald from the University of Alberta in Edmonton where she has gnomically characterizes human islets from the Alberta Islet Core.  These data have been made publicly available through multiple controlled access databases including the European Genome-Phenome Atlas (EGA) and the Translational Human Pancreatic Islet Genotype Tissue-Expression Resource (TIGER)  enabling their use by multiple research groups.  

Her work has direct translational relevance evidenced by roles on both the ClinGen Expert Review Group for Variant Curation for Monogenic Diabetes and role as chair and co-lead for Precision Diagnostics in Monogenic Diabetes for the American Diabetes Association & European Association for the Study of Diabetes Precision Medicine Working group.

She has been an active part of the Stanford Diabetes Research Center since joining the faculty here in 2020 as co-lead of the Pancreas and Islet Biology Affinity group, a user of the Islet Research and Immune Monitoring Cores, a previous recipient of a P&F Award, and collaborator with many SDRC members.