Sara Michie

Sara Michie, MD, Professor, Department of Pathology, Stanford University School of Medicine

Research Description: Dr. Michie’s research program over the past 30 years has focused on defining the molecular mechanisms that control the migration of T cells from blood vessels into secondary lymphoid tissues and target tissues. She has focused on autoimmune diseases in humans and in mouse models of human autoimmune diseases, including type 1 diabetes mellitus (T1D). In addition, Dr. Michie is a board certified anatomic pathologist with expertise in human and rodent histopathology and immunohistology.

Selected relevant publications (Stanford DRC members in BOLD):

1. Xu B, Cook RE, and Michie SA. Alpha4beta7 integrin/MAdCAM-1 adhesion pathway is crucial for B cell migration into pancreatic lymph nodes in nonobese diabetic mice. J Autoimmun 35:124-129, 2010.

2. Shan Z, Xu BH, Mikulowska-Mennis A, and Michie SA. CCR7 Directs the Recruitment of T Cells into Inflamed Pancreatic Islets of Nonobese Diabetic (NOD) Mice. Immunol Res 58:351-357, 2014.

3. Hamilton DC, Shih HH, Schubert RA, Michie SA, Staats PN, Kaplan DL, and Fontaine MJ. A silk-based Encapsulation Platform for Pancreatic Islet Transplantation Improves Islet Function In Vivo. J Tissue Eng Regen Med doi: 10.1002/term. 2015.