Tracey McLaughlin

Tracey McLaughlin, MD, MS, Professor, Department of Medicine, Division of Endocrinology, Gerontology and Metabolism, Stanford University School of Medicine 

Research Description: Dr. McLaughlin’s research program over the past 18 years has made important contributions to our understanding of the relationship been obesity and insulin resistance. Early studies defined the metabolic heterogeneity in overweight to moderately obese individuals and characterized responses in cardiometabolic risk factors to various dietary interventions. More recent studies include detailed analyses of adipose tissue/cells and how they respond to dietary and weight loss/gain manipulations. Her laboratory is actively committed to collaborating with multiple basic science laboratories at Stanford to yield innovative and transformative research related to the biology of human adipose tissue and its role in insulin resistance.

Selected relevant publications (Stanford DRC Members in BOLD):

  1. Tan M, Lamendola C, Luong R, McLaughlin T, Craig C. Safety, efficacy and pharmacokinetics of repeat subcutaneous dosing of avexitide (exendin 9-39) for treatment of post-bariatric hypoglycaemia. Diabetes Obes Metab. 2020 Aug;22(8):1406-1416. doi: 10.1111/dom.14048. PMID: 32250530. 

  2. Allister-Price C, Craig CM, Spielman D, Cushman SS, McLaughlin TL. Metabolic markers, regional adiposity, and adipose cell size: relationship to insulin resistance in African-American as compared with Caucasian women. Int J Obes (Lond). 2019 Jun;43(6):1164-1173. doi: 10.1038/s41366-018-0191-1. PMID: 30127463; PMCID: PMC6382609. 

  3. Fathzadeh M, Li J, Rao A, Cook N, Chennamsetty I, Seldin M, Zhou X, Sangwung P, Gloudemans MJ, Keller M, Attie A, Yang J, Wabitsch M, Carcamo-Orive I, Tada Y, Lusis AJ, Shin MK, Molony CM, McLaughlin T, Reaven G, Montgomery SB, Reilly D, Quertermous T, Ingelsson E, Knowles JW. FAM13A affects body fat distribution and adipocyte function. Nat Commun. 2020 Mar 19;11(1):1465. doi: 10.1038/s41467-020-15291-z. PMID: 32193374; PMCID: PMC7081215. 

  4. Nagy N, Sunkari VG, Kaber G, Hasbun S, Lam DN, Speake C, Sanda S, McLaughlin TL, Wight TN, Long SR, Bollyky PL. Hyaluronan levels are increased systemically in human type 2 but not type 1 diabetes independently of glycemic control. Matrix Biol. 2019 Jul;80:46-58. doi: 10.1016/j.matbio.2018.09.003. PMID: 30196101; PMCID: PMC6401354.