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Got Oxygen? Dr. Avnesh Thakor's bioscaffolds make sure islets never go without.
Islet transplantation is an effective form of therapy for type 1 diabetics, however, lack of oxygen in transplanted islets decreases their survival and function over time. SDRC researcher Dr. Avnesh Thakor's group addressed the problem of oxygen accessibility by creating an innovative, transplantable bioscaffold for islets that makes its own oxygen. This work was featured on the back cover of Advanced Functional Materials and represents a milestone in having the potential to greatly improve the efficacy of islet transplantation therapy.
SDRC member, Dr. Eric Appel, creates a new insulin formulation for better glucose control
Researchers have developed a way to combine insulin with a second hormone known as amylin, to create a two-in-one injection that could, if proven safe and effective in human trials, make it easier for diabetics to more effectively control their blood sugar levels.
SDRC New Member Spotlight: Dr. Danny Chou
“A game changer” is how SDRC’s newest member, Dr. Danny Chou describes the development of Smart Insulin, a type of insulin formulation that can maintain normal blood sugar levels without the accompanying risk of hypoglycemia.
SDRC member, Dr. Joyce Liao is director of the newly established Stanford Health Care Center for Optic Disc Drusen
As a bespectacled second-grader, Sam Hickman was undergoing an annual eye exam when his optometrist noticed that his optic nerves looked “lumpy-bumpy” — a telltale sign of optic disc drusen (ODD).
SDRC member, Dr. David Scheinker’s dashboard to estimate the COVID hospitalization rate at the county level
Input the number of COVID-19 cases, the rate at which they spread, and the impact of an intervention to estimate the number of people requiring hospitalization.
A decade-long study finds that roughly 1 in 10 people carry genetic variants that may blunt the blood sugar-lowering effects of widely used diabetes medications — raising new questions about precision medicine in diabetes care. Read more...