Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis. Lee B, Namkoong H, Yang Y, Huang H, Heller D, Szot GL, Davis MM, Husain SZ, Pandol SJ, Bellin MD, Habtezion A. Gut. 2022 Sep;71(9):1831-1842. doi: 10.1136/gutjnl-2021-324546. Epub 2021 Oct 26. PMID: 34702715; PMCID: PMC9105403.

Robust identification of temporal biomarkers in longitudinal omics studies. Metwally AA, Zhang T, Wu S, Kellogg R, Zhou W, Contrepois K, Tang H, Snyder M. Bioinformatics. 2022 Aug 2;38(15):3802-3811. doi: 10.1093/bioinformatics/btac403. PMID: 35762936; PMCID: PMC9344853.

Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses. Ang LT, Nguyen AT, Liu KJ, Chen A, Xiong X, Curtis M, Martin RM, Raftry BC, Ng CY, Vogel U, Lander A, Lesch BJ, Fowler JL, Holman AR, Chai T, Vijayakumar S, Suchy FP, Nishimura T, Bhadury J, Porteus MH, Nakauchi H, Cheung C, George SC, Red-Horse K, Prescott JB, Loh KM. Cell. 2022 Jul 7;185(14):2523-2541.e30. doi: 10.1016/j.cell.2022.05.024. Epub 2022 Jun 22. PMID: 35738284; PMCID: PMC9617591.

Lymph node colonization induces tumor-immune tolerance to promote distant metastasis. Reticker-Flynn NE, Zhang W, Belk JA, Basto PA, Escalante NK, Pilarowski GOW, Bejnood A, Martins MM, Kenkel JA, Linde IL, Bagchi S, Yuan R, Chang S, Spitzer MH, Carmi Y, Cheng J, Tolentino LL, Choi O, Wu N, Kong CS, Gentles AJ, Sunwoo JB, Satpathy AT, Plevritis SK, Engleman EG. Cell. 2022 May 26;185(11):1924-1942.e23. doi: 10.1016/j.cell.2022.04.019. Epub 2022 May 6. PMID: 35525247; PMCID: PMC9149144.

Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis. Zhang S, Cooper-Knock J, Weimer AK, Shi M, Moll T, Marshall JNG, Harvey C, Nezhad HG, Franklin J, Souza CDS, Ning K, Wang C, Li J, Dilliott AA, Farhan S, Elhaik E, Pasniceanu I, Livesey MR, Eitan C, Hornstein E, Kenna KP; Project MinE ALS Sequencing Consortium, Veldink JH, Ferraiuolo L, Shaw PJ, Snyder MP. Neuron. 2022 Mar 16;110(6):992-1008.e11. doi: 10.1016/j.neuron.2021.12.019. Epub 2022 Jan 18. PMID: 35045337; PMCID: PMC9017397.

Pre-clinical development and molecular characterization of an engineered type 1 regulatory T-cell product suitable for immunotherapy. Liu JM, Chen P, Uyeda MJ, Cieniewicz B, Sayitoglu EC, Thomas BC, Sato Y, Bacchetta R, Cepika AM, Roncarolo MG. Cytotherapy. 2021 Nov;23(11):1017-1028. doi: 10.1016/j.jcyt.2021.05.010. Epub 2021 Aug 15. PMID: 34404616; PMCID: PMC8546780.

Alloantigen-specific type 1 regulatory T cells suppress through CTLA-4 and PD-1 pathways and persist long-term in patients. Chen PP, Cepika AM, Agarwal-Hashmi R, Saini G, Uyeda MJ, Louis DM, Cieniewicz B, Narula M, Amaya Hernandez LC, Harre N, Xu L, Thomas BC, Ji X, Shiraz P, Tate KM, Margittai D, Bhatia N, Meyer E, Bertaina A, Davis MM, Bacchetta R, Roncarolo MG. Sci Transl Med. 2021 Oct 27;13(617):eabf5264. doi: 10.1126/scitranslmed.abf5264. Epub 2021 Oct 27. PMID: 34705520; PMCID: PMC9451143.

Evolution of Cytomegalovirus-Responsive T Cell Clonality following Solid Organ Transplantation. Higdon LE, Schaffert S, Huang H, Montez-Rath ME, Lucia M, Jha A, Saligrama N, Margulies KB, Martinez OM, Davis MM, Khatri P, Maltzman JS. J Immunol. 2021 Oct 15;207(8):2077-2085. doi: 10.4049/jimmunol.2100404. Epub 2021 Sep 22. PMID: 34551964; PMCID: PMC8492537.

Functional Consequences of Memory Inflation after Solid Organ Transplantation. Higdon LE, Schaffert S, Cohen RH, Montez-Rath ME, Lucia M, Saligrama N, Margulies KB, Martinez OM, Tan JC, Davis MM, Khatri P, Maltzman JS. J Immunol. 2021 Oct 15;207(8):2086-2095. doi: 10.4049/jimmunol.2100405. Epub 2021 Sep 22. PMID: 34551963; PMCID: PMC8492533.

Disrupting biological sensors of force promotes tissue regeneration in large organisms. Chen K, Kwon SH, Henn D, Kuehlmann BA, Tevlin R, Bonham CA, Griffin M, Trotsyuk AA, Borrelli MR, Noishiki C, Padmanabhan J, Barrera JA, Maan ZN, Dohi T, Mays CJ, Greco AH, Sivaraj D, Lin JQ, Fehlmann T, Mermin-Bunnell AM, Mittal S, Hu MS, Zamaleeva AI, Keller A, Rajadas J, Longaker MT, Januszyk M, Gurtner GC. Nat Commun. 2021 Sep 6;12(1):5256. doi: 10.1038/s41467-021-25410-z. PMID: 34489407; PMCID: PMC8421385.

Disrupting biological sensors of force promotes tissue regeneration in large organisms. Chen K, Kwon SH, Henn D, Kuehlmann BA, Tevlin R, Bonham CA, Griffin M, Trotsyuk AA, Borrelli MR, Noishiki C, Padmanabhan J, Barrera JA, Maan ZN, Dohi T, Mays CJ, Greco AH, Sivaraj D, Lin JQ, Fehlmann T, Mermin-Bunnell AM, Mittal S, Hu MS, Zamaleeva AI, Keller A, Rajadas J, Longaker MT, Januszyk M, Gurtner GC. Nat Commun. 2021 Sep 6;12(1):5256. doi: 10.1038/s41467-021-25410-z. PMID: 34489407; PMCID: PMC8421385.

Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion. Wu CT, Hilgendorf KI, Bevacqua RJ, Hang Y, Demeter J, Kim SK, Jackson PK. Genes Dev. 2021 Sep 1;35(17-18):1243-1255. doi: 10.1101/gad.348261.121. Epub 2021 Aug 12. PMID: 34385262; PMCID: PMC8415323.

Longitudinal linked-read sequencing reveals ecological and evolutionary responses of a human gut microbiome during antibiotic treatment. Roodgar M, Good BH, Garud NR, Martis S, Avula M, Zhou W, Lancaster SM, Lee H, Babveyh A, Nesamoney S, Pollard KS, Snyder MP. Genome Res. 2021 Aug;31(8):1433-1446. doi: 10.1101/gr.265058.120. Epub 2021 Jul 22. PMID: 34301627; PMCID: PMC8327913.

Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging. Rovira-Clavé X, Jiang S, Bai Y, Zhu B, Barlow G, Bhate S, Coskun AF, Han G, Ho CK, Hitzman C, Chen SY, Bava FA, Nolan GP. Nat Commun. 2021 Jul 30;12(1):4628. doi: 10.1038/s41467-021-24822-1. PMID: 34330905; PMCID: PMC8324837.

Skeletal stem and progenitor cells maintain cranial suture patency and prevent craniosynostosis. Menon S, Salhotra A, Shailendra S, Tevlin R, Ransom RC, Januszyk M, Chan CKF, Behr B, Wan DC, Longaker MT, Quarto N. Nat Commun. 2021 Jul 30;12(1):4640. doi: 10.1038/s41467-021-24801-6. PMID: 34330896; PMCID: PMC8324898.

An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging. Sayed N, Huang Y, Nguyen K, Krejciova-Rajaniemi Z, Grawe AP, Gao T, Tibshirani R, Hastie T, Alpert A, Cui L, Kuznetsova T, Rosenberg-Hasson Y, Ostan R, Monti D, Lehallier B, Shen-Orr SS, Maecker HT, Dekker CL, Wyss-Coray T, Franceschi C, Jojic V, Haddad F, Montoya JG, Wu JC, Davis MM, Furman D. Nat Aging. 2021 Jul;1:598-615. doi: 10.1038/s43587-021-00082-y. Epub 2021 Jul 12. PMID: 34888528; PMCID: PMC8654267.

Pancreatic Pseudoislets: An Organoid Archetype for Metabolism Research. Friedlander MSH, Nguyen VM, Kim SK, Bevacqua RJ. Diabetes. 2021 May;70(5):1051-1060. doi: 10.2337/db20-1115. Epub 2021 May 4. PMID: 33947722; PMCID: PMC8343609.