Yan Hang PhD., Senior research scientist: Core manager
Dr. Hang establishes standard operating procedures (SOPs) for all core services and provides expertise for planning of experiments and projects related to islet biology. Dr. Hang trained with Dr. Roland Stein at Vanderbilt University in her doctoral studies of transcriptional regulation in islets, then was a post-doctoral fellow with Mark Kay and Seung Kim at Stanford, prior to becoming the SIRC manager. She is an expert in multiple facets of islet biology relevant to this core, including islet functional assays, immunohistology, molecular biology, viral targeting of human and mouse islet cells and human pseudoislet development, chromatin and genome biology (including bulk and single cell RNA-Seq, ATAC-Seq and pcHi-C), bioinformatics and statistical analysis, and multi-plex imaging technologies like CLARITY and CODEX. She also leads the islet perifusion service in the SIRC. Her experience and expertise are enormously beneficial to SDRC members who consult, train and use services in the SIRC.
Jing Wang, MD., Sr. Scientist
Dr. Wang has broad range experience on diabetes, cancer, and neurological research. He is a core member of stem cell research project, applies differentiated cells and gene edited cells, organoids, islets and tissues to in vivo models. He provides services and training classes on transplantation surgery in small and large animals. Prior to joining Stanford, he was a key member of human diabetes clinical trial program at University of Pennsylvania.
Xueying Gu, M.A., Laboratory Science Research Assistant III
Ms. Gu is an expert in mouse gavage, glucose tolerance testing, mouse islet isolation, islet culture and static-batch incubation, perifusion, immunohistology, and islet transplantation. She routinely performs or trains SDRC members in these procedures.