Yan Hang PhD., Senior research scientist: Core manager
Dr. Hang establishes standard operating procedures (SOPs) for all core services and provides expertise for planning of experiments and projects related to islet biology. Dr. Hang trained with Dr. Roland Stein at Vanderbilt University in her doctoral studies of transcriptional regulation in islets, then was a post-doctoral fellow with Mark Kay and Seung Kim at Stanford, prior to becoming the SIRC manager. She is an expert in multiple facets of islet biology relevant to this core, including islet functional assays, immunohistology, molecular biology, viral targeting of human and mouse islet cells and human pseudoislet development, chromatin and genome biology (including bulk and single cell RNA-Seq, ATAC-Seq and pcHi-C), bioinformatics and statistical analysis, and multi-plex imaging technologies like CLARITY and CODEX. She also leads the islet perifusion service in the SIRC. Her experience and expertise are enormously beneficial to SDRC members who consult, train and use services in the SIRC.
Jing Wang, MD., Laboratory Science Research Assistant III
Dr. Wang has worked at Stanford since 2008 and is a skilled small animal surgeon. He expertly performs and trains others in islet transplantation, islet isolation from mice and islet culture. Prior to joining Stanford he was a key member of the human islet isolation team led by Dr. Ali Naji at University of Pennsylvania. At Stanford he has also performed human islet isolations from cadaveric pancreata. Dr. Wang has served as an invited guest instructor at the Oregon National Primate Research Center, where he successfully trained staff there in islet isolation from pancreata of rhesus monkeys.
Xueying Gu, M.A., Laboratory Science Research Assistant III
Ms. Gu is an expert in mouse gavage, glucose tolerance testing, mouse islet isolation, islet culture and static-batch incubation, perifusion, immunohistology, and islet transplantation. She routinely performs or trains SDRC members in these procedures.