William H. Robinson

William H. Robinson, MD PhD, James W. Raitt, M.D. Professor, Medicine - Immunology & Rheumatology, Stanford University

Research Description:  My lab investigates the role of B cells, antibodies and EBV in autoimmune diseases, with the goal of translating our findings into next generation diagnostics and therapeutics. We have a pilot grant to sequence B cell repertoires and EBV+ B cells in T1D. T1D is an autoimmune disease. EBV is associated with multiple autoimmune diseases including MS, SLE, and RA. We are proposing to investigate whether EBV might play a role in T1D by sequencing EBV+ B Cells in T1D.

Selected relevant publications (Stanford DRC members in BOLD):

1. Baker MC, Sheth K, Liu Y, Lu D, Lu R, Robinson WH. Development of Osteoarthritis in Adults With Type 2 Diabetes Treated With Metformin vs a Sulfonylurea. JAMA Netw Open. 2023 Mar 1;6(3):e233646. doi: 10.1001/jamanetworkopen.2023.3646. PMID: 36939700; PMCID: PMC10028483.

2. Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Dekker CL, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Chien YH, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM. KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Science. 2022 Apr 15;376(6590):eabi9591. doi: 10.1126/science.abi9591. Epub 2022 Apr 15. PMID: 35258337; PMCID: PMC8995031.